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Function
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49 Pathways
- AKT phosphorylates targets in the cytosol,
- Signaling by Rho GTPases,
- Generic Transcription Pathway,
- RNA Polymerase II Transcription,
- Transcriptional Regulation by TP53,
- Signaling by Non-Receptor Tyrosine Kinases,
- Senescence-Associated Secretory Phenotype (SASP),
- FOXO-mediated transcription,
- Diseases of signal transduction by growth factor receptors and second messengers,
- Constitutive Signaling by AKT1 E17K in Cancer,
- Cellular responses to external stimuli,
- PI3K/AKT Signaling in Cancer,
- Signal Transduction,
- G1 Phase,
- PTK6 Regulates Cell Cycle,
- RHO GTPase Effectors,
- PIP3 activates AKT signaling,
- Cyclin A:Cdk2-associated events at S phase entry,
- Signaling by PTK6,
- Cell Cycle Checkpoints,
- TP53 Regulates Transcription of Cell Cycle Genes,
- Extra-nuclear estrogen signaling,
- Disease,
- S Phase,
- FOXO-mediated transcription of cell cycle genes,
- ESR-mediated signaling,
- Cellular Senescence,
- Cell Cycle, Mitotic,
- RHO GTPases activate CIT,
- Gene expression (Transcription),
- p53-Dependent G1/S DNA damage checkpoint,
- p53-Dependent G1 DNA Damage Response,
- SCF(Skp2)-mediated degradation of p27/p21,
- Aberrant regulation of mitotic cell cycle due to RB1 defects,
- Intracellular signaling by second messengers,
- Cellular responses to stress,
- TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest,
- DNA Damage/Telomere Stress Induced Senescence,
- G1/S DNA Damage Checkpoints,
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3),
- Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects,
- G1/S Transition,
- Cyclin E associated events during G1/S transition ,
- Diseases of mitotic cell cycle,
- Estrogen-dependent nuclear events downstream of ESR-membrane signaling,
- Cell Cycle,
- Signaling by Nuclear Receptors,
- Cyclin D associated events in G1,
- Mitotic G1 phase and G1/S transition
Gene --> GO terms.
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Genomics
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Gene --> Chromosomal location.
Gene --> GO terms.
Gene --> Overlapping genes.
Disease
Gene (Hum OR Rat) --> Mouse Allele (Phenotype)
Gene --> Alleles and Disease (clinVar data)
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Other
49 Pathways
- AKT phosphorylates targets in the cytosol,
- Signaling by Rho GTPases,
- Generic Transcription Pathway,
- RNA Polymerase II Transcription,
- Transcriptional Regulation by TP53,
- Signaling by Non-Receptor Tyrosine Kinases,
- Senescence-Associated Secretory Phenotype (SASP),
- FOXO-mediated transcription,
- Diseases of signal transduction by growth factor receptors and second messengers,
- Constitutive Signaling by AKT1 E17K in Cancer,
- Cellular responses to external stimuli,
- PI3K/AKT Signaling in Cancer,
- Signal Transduction,
- G1 Phase,
- PTK6 Regulates Cell Cycle,
- RHO GTPase Effectors,
- PIP3 activates AKT signaling,
- Cyclin A:Cdk2-associated events at S phase entry,
- Signaling by PTK6,
- Cell Cycle Checkpoints,
- TP53 Regulates Transcription of Cell Cycle Genes,
- Extra-nuclear estrogen signaling,
- Disease,
- S Phase,
- FOXO-mediated transcription of cell cycle genes,
- ESR-mediated signaling,
- Cellular Senescence,
- Cell Cycle, Mitotic,
- RHO GTPases activate CIT,
- Gene expression (Transcription),
- p53-Dependent G1/S DNA damage checkpoint,
- p53-Dependent G1 DNA Damage Response,
- SCF(Skp2)-mediated degradation of p27/p21,
- Aberrant regulation of mitotic cell cycle due to RB1 defects,
- Intracellular signaling by second messengers,
- Cellular responses to stress,
- TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest,
- DNA Damage/Telomere Stress Induced Senescence,
- G1/S DNA Damage Checkpoints,
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3),
- Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects,
- G1/S Transition,
- Cyclin E associated events during G1/S transition ,
- Diseases of mitotic cell cycle,
- Estrogen-dependent nuclear events downstream of ESR-membrane signaling,
- Cell Cycle,
- Signaling by Nuclear Receptors,
- Cyclin D associated events in G1,
- Mitotic G1 phase and G1/S transition
