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Gene : CDKN2C Homo sapiens

Name  ? cyclin dependent kinase inhibitor 2C Cytological Location  1p32.3
Brief Description  cyclin dependent kinase inhibitor 2C
Description  The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000008046,
  • HGNC:1789,
  • p18,
  • cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4),
  • CDKN2C,
  • uc057gkh.1,
  • p18-INK4C,
  • NM_001262,
  • INK4C,
  • BC000598,
  • INK4C,
  • p18
  • identifiers:
  • 1031,
  • ENSG00000123080,
  • CDKN2C

Genome feature

Region: gene ? Length: 5929  
Location: 1:50968706-50974634 Cyto location: 1p32.3


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Disease

0 Diseases

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Expression

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Other

885 SNPs

5 Cross References

17 Data Sets

1 Homologues

0 Located Features

97 Rna Seq Results