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Gene : CDKN2D Homo sapiens

Name  ? cyclin dependent kinase inhibitor 2D Cytological Location  19p13.2
Brief Description  cyclin dependent kinase inhibitor 2D
Description  The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]
  • synonyms:
  • p19,
  • INK4D,
  • p19,
  • uc002mpa.4,
  • p19-INK4D,
  • NM_079421,
  • cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4),
  • OTTHUMG00000180583,
  • INK4D,
  • CDKN2D,
  • HGNC:1790
  • identifiers:
  • 1032,
  • ENSG00000129355,
  • CDKN2D

Genome feature

Region: gene ? Length: 2520  
Location: 19:10566460-10568979 reverse strand Cyto location: 19p13.2

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0 Diseases

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3740 SNPs

5 Cross References

15 Data Sets

1 Homologues

0 Located Features

97 Rna Seq Results