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Gene : BAIAP2 Homo sapiens

Name  ? BAR/IMD domain containing adaptor protein 2 Cytological Location  17q25.3
Brief Description  BAR/IMD domain containing adaptor protein 2
Description  The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
  • synonyms:
  • WAML,
  • OTTHUMG00000177698,
  • BAP2,
  • uc002jzg.3,
  • IRSp53,
  • BAIAP2,
  • FLAF3,
  • NM_001144888,
  • WASP and MIM like,
  • BAP2,
  • IRSP53,
  • AB015019,
  • WAML,
  • HGNC:947,
  • BAI1 associated protein 2,
  • insulin receptor substrate of 53 kDa
  • identifiers:
  • 10458,
  • ENSG00000175866,
  • BAIAP2

Genome feature

Region: gene ? Length: 82304  
Location: 17:81035131-81117434 Cyto location: 17q25.3

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0 Diseases

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851 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results