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Gene : CEBPA Homo sapiens

Name  ? CCAAT enhancer binding protein alpha Cytological Location  19q13.11
Brief Description  CCAAT enhancer binding protein alpha
Description  This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013]
  • synonyms:
  • CCAAT/enhancer binding protein alpha,
  • NM_004364,
  • C/EBP-alpha,
  • C/EBP-alpha,
  • OTTHUMG00000161461,
  • CEBPA,
  • CEBP,
  • HGNC:1833,
  • CEBP,
  • M37197,
  • CCAAT/enhancer binding protein (C/EBP), alpha,
  • uc002nun.4
  • identifiers:
  • 1050,
  • ENSG00000245848,
  • CEBPA

Genome feature

Region: gene ? Length: 2631  
Location: 19:33299934-33302564 reverse strand Cyto location: 19q13.11


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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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Expression

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Other

329 SN Ps

5 Cross References

18 Data Sets

11 Homologues

0 Located Features

97 Rna Seq Results