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Gene : CEL Homo sapiens

Name  ? carboxyl ester lipase Cytological Location  9q34.13
Brief Description  carboxyl ester lipase
Description  The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq, Jul 2008]
  • synonyms:
  • M54994,
  • MODY8,
  • CEase,
  • MODY8,
  • bile salt-stimulated lipase,
  • BAL,
  • NM_001807,
  • HGNC:1848,
  • BSDL,
  • FAP,
  • CEL,
  • FAPP,
  • BSSL,
  • BSSL,
  • CELL,
  • OTTHUMG00000020855,
  • uc010naa.3,
  • LIPA
  • identifiers:
  • 1056,
  • ENSG00000170835,
  • CEL

Genome feature

Region: gene ? Length: 9881  
Location: 9:133061981-133071861 Cyto location: 9q34.13

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

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Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

87 SN Ps

5 Cross References

18 Data Sets

12 Homologues

0 Located Features

97 Rna Seq Results