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Gene : CENPA Homo sapiens

Name  ? centromere protein A Cytological Location  2p23.3
Brief Description  centromere protein A
Description  Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015]
  • synonyms:
  • centromere protein A, 17kDa,
  • CenH3,
  • uc002rhr.4,
  • CenH3,
  • U14518,
  • histone H3-like centromeric protein A,
  • OTTHUMG00000097073,
  • centromere protein A (17kD),
  • CENPA,
  • HGNC:1851,
  • centromere-specific histone,
  • CENP-A,
  • CENP-A,
  • NM_001809
  • identifiers:
  • 1058,
  • ENSG00000115163,

Genome feature

Region: gene ? Length: 8534  
Location: 2:26786056-26794589 Cyto location: 2p23.3

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0 Diseases

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779 SNPs

5 Cross References

15 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results