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Gene : CENPE Homo sapiens

Name  ? centromere protein E Cytological Location  4q24
Brief Description  centromere protein E
Description  Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Nov 2014]
  • synonyms:
  • OTTHUMG00000160980,
  • PPP1R61,
  • PPP1R61,
  • centromere protein E, 312kDa,
  • KIF10,
  • uc003hxb.1,
  • HGNC:1856,
  • Z15005,
  • KIF10,
  • CENPE,
  • MCPH13,
  • protein phosphatase 1, regulatory subunit 61,
  • CENP-E,
  • NM_001286734,
  • centromere protein E (312kD)
  • identifiers:
  • 1062,
  • ENSG00000138778,
  • CENPE

Genome feature

Region: gene ? Length: 92598  
Location: 4:103105811-103198408 reverse strand Cyto location: 4q24


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Disease

1 Diseases

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3753 SN Ps

5 Cross References

19 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results