help  | about  | cite  | software

Gene : CENPE Homo sapiens

Name  ? centromere protein E Cytological Location  4q24
Brief Description  centromere protein E
Description  Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Nov 2014]
  • synonyms:
  • OTTHUMG00000160980,
  • PPP1R61,
  • PPP1R61,
  • centromere protein E, 312kDa,
  • KIF10,
  • uc003hxb.1,
  • HGNC:1856,
  • Z15005,
  • KIF10,
  • CENPE,
  • MCPH13,
  • protein phosphatase 1, regulatory subunit 61,
  • CENP-E,
  • NM_001286734,
  • centromere protein E (312kD)
  • identifiers:
  • 1062,
  • ENSG00000138778,

Genome feature

Region: gene ? Length: 92598  
Location: 4:103105811-103198408 reverse strand Cyto location: 4q24

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

19 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results