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Gene : CENPF Homo sapiens

Name  ? centromere protein F Cytological Location  1q41
Brief Description  centromere protein F
Description  This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000036955,
  • hcp-1,
  • PRO1779,
  • hcp-1,
  • centromere protein F, 350/400kDa (mitosin),
  • CILD31,
  • centromere protein F, 350/400kDa,
  • CENF,
  • mitosin,
  • U30872,
  • NM_016343,
  • uc001hkm.4,
  • CENPF,
  • HGNC:1857
  • identifiers:
  • 1063,
  • ENSG00000117724,

Genome feature

Region: gene ? Length: 61377  
Location: 1:214603195-214664571 Cyto location: 1q41

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1 Diseases

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95 SNPs

5 Cross References

19 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results