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Gene : CAMKK2 Homo sapiens

Name  ? calcium/calmodulin dependent protein kinase kinase 2 Cytological Location  12q24.31
Brief Description  calcium/calmodulin dependent protein kinase kinase 2
Description  The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012]
  • synonyms:
  • CAMKK2,
  • OTTHUMG00000169156,
  • uc001tzv.4,
  • KIAA0787,
  • calcium/calmodulin-dependent protein kinase kinase beta,
  • calcium/calmodulin-dependent protein kinase kinase 2, beta,
  • AF101264,
  • CAMKK,
  • NM_172226,
  • HGNC:1470,
  • MGC15254,
  • identifiers:
  • 10645,
  • ENSG00000110931,
  • CAMKK2

Genome feature

Region: gene ? Length: 60128  
Location: 12:121237692-121297819 reverse strand Cyto location: 12q24.31

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3740 SNPs

5 Cross References

17 Data Sets

4 Homologues

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97 Rna Seq Results