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Gene : CES1 Homo sapiens

Name  ? carboxylesterase 1 Cytological Location  16q12.2
Brief Description  carboxylesterase 1
Description  This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
  • synonyms:
  • NM_001266,
  • CES2,
  • CE-1,
  • REH,
  • CES1A2,
  • ACAT,
  • BC012418,
  • OTTHUMG00000176718,
  • hCE-1,
  • CEH,
  • TGH,
  • uc002eil.4,
  • HMSE1,
  • HMSE,
  • carboxylesterase 1 (monocyte/macrophage serine esterase 1),
  • SES1,
  • PCE-1,
  • CEH,
  • CES1,
  • HMSE,
  • CES2,
  • SES1,
  • HGNC:1863,
  • HMSE1,
  • human monocyte/macrophage serine esterase 1,
  • CES1A1
  • identifiers:
  • 1066,
  • ENSG00000198848,
  • CES1

Genome feature

Region: gene ? Length: 30277  
Location: 16:55802851-55833127 reverse strand Cyto location: 16q12.2


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Disease

1 Diseases

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3756 SN Ps

5 Cross References

18 Data Sets

34 Homologues

0 Located Features

97 Rna Seq Results