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Gene : CORIN Homo sapiens

Name  ? corin, serine peptidase Cytological Location  4p12
Brief Description  corin, serine peptidase
Description  This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
  • synonyms:
  • OTTHUMG00000099441,
  • AF133845,
  • PRSC,
  • CRN,
  • PEE5,
  • HGNC:19012,
  • ATC2,
  • NM_001278585,
  • Lrp4,
  • uc003gxm.5,
  • CRN,
  • TMPRSS10,
  • Lrp4,
  • corin, serine protease,
  • TMPRSS10,
  • CORIN,
  • ATC2
  • identifiers:
  • 10699,
  • ENSG00000145244,
  • CORIN

Genome feature

Region: gene ? Length: 244109  
Location: 4:47593998-47838106 reverse strand Cyto location: 4p12


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

3753 SN Ps

4 Cross References

15 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results