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Gene : CETN3 Homo sapiens

Name  ? centrin 3 Cytological Location  5q14.3
Brief Description  centrin 3
Description  The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
  • synonyms:
  • centrin, EF-hand protein, 3 (CDC31 yeast homolog),
  • CDC31 yeast homolog,
  • NM_004365,
  • OTTHUMG00000131326,
  • EF-hand superfamily member,
  • CEN3,
  • Y12473,
  • CDC31,
  • CEN3,
  • uc003kjo.4,
  • HGNC:1868,
  • CETN3,
  • centrin, EF-hand protein, 3
  • identifiers:
  • 1070,
  • ENSG00000153140,
  • CETN3

Genome feature

Region: gene ? Length: 17500  
Location: 5:90392257-90409756 reverse strand Cyto location: 5q14.3

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

274 SNPs

5 Cross References

15 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results