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Gene : 107126288 Homo sapiens

Description  This region is known to undergo somatic cell DNA recombination with another region, the nucleoporin 98kDa (NUP98) recombination region, located on the p arm of chromosome 11. Recombination between these two regions results in a translocation known as the t(7;11)(p15;p15) rearrangement, and can produce in-frame gene fusions involving the nucleoporin 98kDa (NUP98) gene and the homeobox A13 (HOXA13) gene. NUP98-HOXA13 fusion transcripts have been observed in some individuals with chronic myeloid leukemia (CML), acute myelogenous leukemia (AML) and myelodysplastic syndrome (MDS). Multiple NUP98-HOXA13 fusion transcripts have been described, differing in the NUP98 exon combination present. These differences are thought to be the result of differences in the site of recombination. [provided by RefSeq, Mar 2017]
  • identifiers:
  • 107126288

Genome feature

Region: gene ?
Location: No location information in HumanMine


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

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Disease

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Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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1 Data Sets

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