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Gene : CERS1 Homo sapiens

Name  ? ceramide synthase 1 Cytological Location  19p13.11
Brief Description  ceramide synthase 1
Description  This gene encodes a ceramide synthase enzyme, which catalyzes the synthesis of ceramide, the hydrophobic moiety of sphingolipids. The encoded enzyme synthesizes 18-carbon (C18) ceramide in brain neurons. Elevated expression of this gene may be associated with increased longevity, while decreased expression of this gene may be associated with myoclonus epilepsy with dementia in human patients. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1. [provided by RefSeq, Jul 2016]
  • synonyms:
  • GDF1,
  • LAG1 longevity assurance homolog 1 (S. cerevisiae),
  • LASS1,
  • CERS1,
  • LASS1,
  • UOG1,
  • OTTHUMG00000183049,
  • EPM8,
  • LAG1,
  • HGNC:14253,
  • NM_001290265,
  • LAG1,
  • GDF-1,
  • longevity assurance (LAG1, S. cerevisiae) homolog 1,
  • UOG1,
  • LAG1 homolog, ceramide synthase 1,
  • AF105005,
  • uc060vul.1
  • identifiers:
  • 10715,
  • ENSG00000223802,
  • CERS1

Genome feature

Region: gene ? Length: 28438  
Location: 19:18868545-18896982 reverse strand Cyto location: 19p13.11

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1 Diseases

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544 SNPs

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results