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Gene : CAPN9 Homo sapiens

Name  ? calpain 9 Cytological Location  1q42.2
Brief Description  calpain 9
Description  Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • GC36,
  • OTTHUMG00000037779,
  • GC36,
  • AF022799,
  • NM_006615,
  • HGNC:1486,
  • calpain 9 (nCL-4),
  • nCL-4,
  • nCL-4,
  • novel calpain large subunit-4,
  • CAPN9,
  • uc001htz.2
  • identifiers:
  • 10753,
  • ENSG00000135773,
  • CAPN9

Genome feature

Region: gene ? Length: 56068  
Location: 1:230747289-230803356 Cyto location: 1q42.2


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

3756 SN Ps

5 Cross References

14 Data Sets

16 Homologues

0 Located Features

97 Rna Seq Results