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Gene : CYSLTR1 Homo sapiens

Name  ? cysteinyl leukotriene receptor 1 Cytological Location  Xq21.1
Brief Description  cysteinyl leukotriene receptor 1
Description  This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  • synonyms:
  • OTTHUMG00000021889,
  • CYSLT1R,
  • CYSLT1R,
  • HGNC:17451,
  • AF119711,
  • uc010nmb.5,
  • HMTMF81,
  • CYSLTR1,
  • CysLT(1),
  • CysLT1,
  • NM_001282186,
  • CYSLT1
  • identifiers:
  • 10800,
  • ENSG00000173198,

Genome feature

Region: gene ? Length: 56144  
Location: X:78271468-78327611 reverse strand Cyto location: Xq21.1

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3740 SNPs

5 Cross References

16 Data Sets

11 Homologues

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97 Rna Seq Results