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Gene : CCR9 Homo sapiens

Name  ? C-C motif chemokine receptor 9 Cytological Location  3p21.31
Brief Description  C-C motif chemokine receptor 9
Description  The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
  • synonyms:
  • CDw199,
  • NM_001256369,
  • GPR28,
  • uc003coz.3,
  • HGNC:1610,
  • GPR-9-6,
  • GPR-9-6,
  • CCR9,
  • OTTHUMG00000133450,
  • AJ132337,
  • CC-CKR-9,
  • GPR28,
  • chemokine (C-C motif) receptor 9,
  • CDw199
  • identifiers:
  • 10803,
  • ENSG00000173585,
  • CCR9

Genome feature

Region: gene ? Length: 17111  
Location: 3:45886064-45903174 Cyto location: 3p21.31


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Disease

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Other

398 SN Ps

5 Cross References

16 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results