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Gene : CLPX Homo sapiens

Name  ? caseinolytic mitochondrial matrix peptidase chaperone subunit X Cytological Location  15q22.31
Brief Description  caseinolytic mitochondrial matrix peptidase chaperone subunit X
Description  The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]
  • synonyms:
  • ClpX caseinolytic protease X homolog (E. coli),
  • ClpX (caseinolytic protease X, E. coli) homolog,
  • CLPX,
  • OTTHUMG00000133139,
  • NM_006660,
  • uc002aom.4,
  • HGNC:2088,
  • EPP2,
  • AJ006267
  • identifiers:
  • 10845,
  • ENSG00000166855,
  • CLPX

Genome feature

Region: gene ? Length: 37156  
Location: 15:65148219-65185374 reverse strand Cyto location: 15q22.31

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

59 SN Ps

5 Cross References

18 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results