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Gene : CYP46A1 Homo sapiens

Name  ? cytochrome P450 family 46 subfamily A member 1 Cytological Location  14q32.2
Brief Description  cytochrome P450 family 46 subfamily A member 1
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000171510,
  • cytochrome P450, family 46, subfamily A, polypeptide 1,
  • CP46,
  • AF094480,
  • CYP46,
  • HGNC:2641,
  • uc001ygo.4,
  • CYP46,
  • CYP46A1,
  • cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase),
  • NM_006668
  • identifiers:
  • 10858,
  • ENSG00000036530,
  • CYP46A1

Genome feature

Region: gene ? Length: 43060  
Location: 14:99684262-99727321 Cyto location: 14q32.2

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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579 SNPs

5 Cross References

15 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results