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Gene : ADAM28 Homo sapiens

Name  ? ADAM metallopeptidase domain 28 Cytological Location  8p21.2
Brief Description  ADAM metallopeptidase domain 28
Description  This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
  • synonyms:
  • OTTHUMG00000163780,
  • MDCL,
  • eMDC II,
  • NM_021778,
  • MDC-L,
  • MDC-Ls,
  • a disintegrin and metalloproteinase domain 28,
  • AJ242015,
  • MDC-Lm,
  • eMDCII,
  • ADAM23,
  • ADAM 28,
  • ADAM28,
  • HGNC:206,
  • uc003xdy.4,
  • eMDCII
  • identifiers:
  • 10863,
  • ENSG00000042980,
  • ADAM28

Genome feature

Region: gene ? Length: 64975  
Location: 8:24294040-24359014 Cyto location: 8p21.2

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

757 SNPs

5 Cross References

16 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results