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Gene : HCST Homo sapiens

Name  ? hematopoietic cell signal transducer Cytological Location  19q13.12
Brief Description  hematopoietic cell signal transducer
Description  This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • synonyms:
  • DNAX-activation protein 10,
  • OTTHUMG00000048132,
  • AF072844,
  • KAP10,
  • uc002ocl.2,
  • DAP10,
  • PIK3AP,
  • KAP10,
  • phosphoinositide-3-kinase adaptor protein,
  • HGNC:16977,
  • NM_014266,
  • PIK3AP,
  • DKFZP586C1522,
  • DAP10,
  • HCST,
  • kinase assoc pro of ~10kDa
  • identifiers:
  • 10870,
  • ENSG00000126264,
  • HCST

Genome feature

Region: gene ? Length: 2013  
Location: 19:35902365-35904377 Cyto location: 19q13.12

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



54 SN Ps

5 Cross References

15 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results