help  | about  | cite  | software

Gene : CFHR4 Homo sapiens

Name  ? complement factor H related 4 Cytological Location  1q31.3
Brief Description  complement factor H related 4
Description  This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene. [provided by RefSeq, Jan 2011]
  • synonyms:
  • uc009wyy.3,
  • complement factor H-related 4,
  • CFHL4,
  • NM_006684,
  • FHR-4,
  • CFHR4,
  • AJ640130,
  • CFHL4,
  • FHR4,
  • HGNC:16979,
  • FHR4,
  • FHR-4,
  • X98337,
  • OTTHUMG00000036647
  • identifiers:
  • 10877,
  • ENSG00000134365,
  • CFHR4

Genome feature

Region: gene ? Length: 30861  
Location: 1:196888051-196918911 Cyto location: 1q31.3

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



404 SN Ps

5 Cross References

15 Data Sets

12 Homologues

0 Located Features

97 Rna Seq Results