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Gene : CBX1 Homo sapiens

Name  ? chromobox 1 Cytological Location  17q21.32
Brief Description  chromobox 1
Description  This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • synonyms:
  • M31,
  • HP1Hsbeta,
  • uc002ine.4,
  • CBX1,
  • M31,
  • NM_006807,
  • chromobox homolog 1,
  • HP1Hs-beta,
  • MOD1,
  • U35451,
  • OTTHUMG00000150417,
  • p25beta,
  • chromobox homolog 1 (Drosophila HP1 beta),
  • CBX,
  • HP1 beta homolog (Drosophila ),
  • CBX,
  • HP1-BETA,
  • HP1-BETA,
  • HP1Hs-beta,
  • MOD1,
  • HGNC:1551
  • identifiers:
  • 10951,
  • ENSG00000108468,
  • CBX1

Genome feature

Region: gene ? Length: 31420  
Location: 17:48070059-48101478 reverse strand Cyto location: 17q21.32


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Gene -> HPO annotation (Human Phenotype Ontology)

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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Expression

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Other

3753 SN Ps

5 Cross References

16 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results