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Gene : CLP1 Homo sapiens

Name  ? cleavage factor polyribonucleotide kinase subunit 1 Cytological Location  11q12.1
Brief Description  cleavage factor polyribonucleotide kinase subunit 1
Description  This gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
  • synonyms:
  • BC000446,
  • cleavage and polyadenylation factor I subunit 1,
  • hClp1,
  • HEAB,
  • polyribonucleotide 5'-hydroxyl-kinase,
  • CLP1,
  • CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae),
  • hClp1,
  • HEAB,
  • uc001nkw.4,
  • OTTHUMG00000167146,
  • HGNC:16999,
  • ATP/GTPbinding protein,
  • NM_006831
  • identifiers:
  • 10978,
  • ENSG00000172409,
  • CLP1

Genome feature

Region: gene ? Length: 4122  
Location: 11:57657744-57661865 Cyto location: 11q12.1


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Disease

1 Diseases

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444 SN Ps

5 Cross References

20 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results