help  | about  | cite  | software

Gene : CLP1 Homo sapiens

Name  ? cleavage factor polyribonucleotide kinase subunit 1 Cytological Location  11q12.1
Brief Description  cleavage factor polyribonucleotide kinase subunit 1
Description  This gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
  • synonyms:
  • HGNC:16999,
  • hClp1,
  • cleavage and polyadenylation factor I subunit 1,
  • CLP1,
  • CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae),
  • NM_006831,
  • uc001nkw.4,
  • HEAB,
  • BC000446,
  • OTTHUMG00000167146,
  • HEAB,
  • ATP/GTPbinding protein,
  • hClp1,
  • polyribonucleotide 5'-hydroxyl-kinase
  • identifiers:
  • 10978,
  • ENSG00000172409,
  • CLP1

Genome feature

Region: gene ? Length: 4104  
Location: 11:57657762-57661865 Cyto location: 11q12.1

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



444 SN Ps

5 Cross References

19 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results