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Gene : COPS6 Homo sapiens

Name  ? COP9 signalosome subunit 6 Cytological Location  7q22.1
Brief Description  COP9 signalosome subunit 6
Description  The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008]
  • synonyms:
  • COP9 subunit 6 (MOV34 homolog, 34 kD),
  • CSN6,
  • NM_006833,
  • COPS6,
  • BC002520,
  • COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis),
  • uc003usu.4,
  • HGNC:21749,
  • CSN6,
  • OTTHUMG00000154632,
  • MOV34-34KD,
  • MOV34-34KD
  • identifiers:
  • 10980,
  • ENSG00000168090,
  • COPS6

Genome feature

Region: gene ? Length: 3219  
Location: 7:100088969-100092187 Cyto location: 7q22.1

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



794 SN Ps

5 Cross References

16 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results