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Gene : CHKB Homo sapiens

Name  ? choline kinase beta Cytological Location  22q13.33
Brief Description  choline kinase beta
Description  Choline kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to phosphocholine/phosphoethanolamine. This is the first enzyme in the biosynthesis of phosphatidylcholine/phosphatidylethanolamine in all animal cells. The highly purified CKs from mammalian sources and their recombinant gene products have been shown to have EK activity also, indicating that both activities reside on the same protein. The choline kinase-like protein encoded by CHKL belongs to the choline/ethanolamine kinase family; however, its exact function is not known. Read-through transcripts are expressed from this locus that include exons from the downstream CPT1B locus. [provided by RefSeq, Jun 2009]
  • synonyms:
  • AB029886,
  • EK,
  • HGNC:1938,
  • CKB,
  • CKEKB,
  • EKB,
  • CHETK,
  • OTTHUMG00000150275,
  • NM_005198,
  • CHKL,
  • MDCMC,
  • CK,
  • CHKL,
  • CHKB,
  • CHETK,
  • choline kinase-like,
  • uc003bmv.4
  • identifiers:
  • 1120,
  • ENSG00000100288,
  • CHKB

Genome feature

Region: gene ? Length: 3887  
Location: 22:50578963-50582849 reverse strand Cyto location: 22q13.33

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1 Diseases

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3740 SNPs

5 Cross References

18 Data Sets

13 Homologues

0 Located Features

97 Rna Seq Results