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Gene : CHN2 Homo sapiens

Name  ? chimerin 2 Cytological Location  7p14.3
Brief Description  chimerin 2
Description  This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, May 2014]
  • synonyms:
  • CHN2-3,
  • ARHGAP3,
  • ARHGAP3,
  • L29126,
  • chimaerin 2,
  • CHN2,
  • RhoGAP3,
  • beta chimerin,
  • RHOGAP3,
  • OTTHUMG00000023063,
  • NM_004067,
  • HGNC:1944,
  • uc003szz.4,
  • BCH,
  • chimerin (chimaerin) 2
  • identifiers:
  • 1124,
  • ENSG00000106069,
  • CHN2

Genome feature

Region: gene ? Length: 367789  
Location: 7:29146547-29514335 Cyto location: 7p14.3

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Gene -> HPO annotation (Human Phenotype Ontology)

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

6 Cross References

16 Data Sets

5 Homologues

0 Located Features

140 Rna Seq Results