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Gene : EXOC3 Homo sapiens

Name  ? exocyst complex component 3 Cytological Location  5p15.33
Brief Description  exocyst complex component 3
Description  The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]
  • synonyms:
  • SEC6,
  • uc003jba.4,
  • NM_007277,
  • SEC6-like 1 (S. cerevisiae),
  • BC034427,
  • Sec6p,
  • EXOC3,
  • Sec6p,
  • HGNC:30378,
  • SEC6L1,
  • SEC6L1,
  • OTTHUMG00000162205
  • identifiers:
  • 11336,
  • ENSG00000180104,
  • EXOC3

Genome feature

Region: gene ? Length: 24115  
Location: 5:443176-467290 Cyto location: 5p15.33

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results