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Gene : CHRNA3 Homo sapiens

Name  ? cholinergic receptor nicotinic alpha 3 subunit Cytological Location  15q25.1
Brief Description  cholinergic receptor nicotinic alpha 3 subunit
Description  This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
  • synonyms:
  • HGNC:1957,
  • cholinergic receptor, nicotinic, alpha 3 (neuronal),
  • OTTHUMG00000143863,
  • NM_000743,
  • cholinergic receptor, nicotinic alpha 3,
  • cholinergic receptor, nicotinic, alpha polypeptide 3,
  • acetylcholine receptor, nicotinic, alpha 3 (neuronal),
  • NACHRA3,
  • BAIPRCK,
  • PAOD2,
  • uc002bec.4,
  • LNCR2,
  • CHRNA3
  • identifiers:
  • 1136,
  • ENSG00000080644,
  • CHRNA3

Genome feature

Region: gene ? Length: 27945  
Location: 15:78593052-78620996 reverse strand Cyto location: 15q25.1


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SNPs

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Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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Expression

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Other

3753 SN Ps

5 Cross References

20 Data Sets

13 Homologues

0 Located Features

97 Rna Seq Results