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Gene : CHRNA5 Homo sapiens

Name  ? cholinergic receptor nicotinic alpha 5 subunit Cytological Location  15q25.1
Brief Description  cholinergic receptor nicotinic alpha 5 subunit
Description  The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).[provided by RefSeq, Jun 2010]
  • synonyms:
  • NM_000745,
  • HGNC:1959,
  • cholinergic receptor, nicotinic alpha 5,
  • uc002bdy.3,
  • OTTHUMG00000143858,
  • CHRNA5,
  • cholinergic receptor, nicotinic, alpha polypeptide 5,
  • acetylcholine receptor, nicotinic, alpha 5 (neuronal),
  • cholinergic receptor, nicotinic, alpha 5 (neuronal),
  • LNCR2
  • identifiers:
  • 1138,
  • ENSG00000169684,
  • CHRNA5

Genome feature

Region: gene ? Length: 29750  
Location: 15:78565520-78595269 Cyto location: 15q25.1

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

19 Data Sets

13 Homologues

0 Located Features

97 Rna Seq Results