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Gene : CHUK Homo sapiens

Name  ? component of inhibitor of nuclear factor kappa B kinase complex Cytological Location  10q24.31
Brief Description  component of inhibitor of nuclear factor kappa B kinase complex
Description  This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CHUK,
  • TCF16,
  • IKK-alpha,
  • AF009225,
  • I-kappa-B kinase,
  • IKK1,
  • conserved helix-loop-helix ubiquitous kinase,
  • inhibitor of nuclear factor kappa-B kinase subunit alpha,
  • TCF16,
  • IKK1,
  • IKKA,
  • IKK-alpha,
  • NM_001278,
  • IKKA,
  • IkBKA,
  • uc001kqp.4,
  • IKBKA,
  • HGNC:1974,
  • OTTHUMG00000018899
  • identifiers:
  • 1147,
  • ENSG00000213341,
  • CHUK

Genome feature

Region: gene ? Length: 41313  
Location: 10:100188298-100229610 reverse strand Cyto location: 10q24.31

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94 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



94 Pathways

7 SN Ps

5 Cross References

19 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results