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Gene : CIDEA Homo sapiens

Name  ? cell death inducing DFFA like effector a Cytological Location  18p11.21|18
Brief Description  cell death inducing DFFA like effector a
Description  This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq, Aug 2010]
  • synonyms:
  • CIDE-A,
  • NM_001279,
  • CIDE-A,
  • uc002kqt.5,
  • cell death-inducing DFFA-like effector a,
  • HGNC:1976,
  • OTTHUMG00000131691,
  • CIDEA,
  • AF041378
  • identifiers:
  • 1149,
  • ENSG00000176194,

Genome feature

Region: gene ? Length: 23235  
Location: 18:12254361-12277595 Cyto location: 18p11.21|18

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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785 SN Ps

5 Cross References

15 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results