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Gene : CKMT1B Homo sapiens

Name  ? creatine kinase, mitochondrial 1B Cytological Location  15q15.3
Brief Description  creatine kinase, mitochondrial 1B
Description  Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CKMT1B,
  • HGNC:1995,
  • CKMT1,
  • OTTHUMG00000059900,
  • uc001zsc.3,
  • NM_020990,
  • J04469,
  • CKMT,
  • CKMT,
  • UMTCK,
  • CKMT1,
  • UMTCK,
  • AK094322,
  • creatine kinase, mitochondrial 1 (ubiquitous)
  • identifiers:
  • 1159,
  • ENSG00000237289,
  • CKMT1B

Genome feature

Region: gene ? Length: 6550  
Location: 15:43592857-43599406 Cyto location: 15q15.3


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

Gene --> Proteins.

SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

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Other

3753 SN Ps

5 Cross References

16 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results