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Gene : CLNK Homo sapiens

Name  ? cytokine dependent hematopoietic cell linker Cytological Location  4p16.1
Brief Description  cytokine dependent hematopoietic cell linker
Description  MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).[supplied by OMIM, Mar 2008]
  • synonyms:
  • AB032369,
  • HGNC:17438,
  • MIST,
  • OTTHUMG00000160062,
  • mast cell immunoreceptor signal transducer,
  • uc003gmo.5,
  • CLNK,
  • MIST,
  • NM_052964
  • identifiers:
  • 116449,
  • ENSG00000109684,
  • CLNK

Genome feature

Region: gene ? Length: 248459  
Location: 4:10486395-10734853 reverse strand Cyto location: 4p16.1

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

209 SN Ps

5 Cross References

16 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results