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Gene : DCD Homo sapiens

Name  ? dermcidin Cytological Location  12q13.2
Brief Description  dermcidin
Description  This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
  • synonyms:
  • DSEP,
  • uc001sgj.4,
  • AF144011,
  • AIDD,
  • HCAP,
  • AIDD,
  • DSEP,
  • OTTHUMG00000169937,
  • PIF,
  • HGNC:14669,
  • survival promoting peptide,
  • DCD-1,
  • proteolysis inducing factor,
  • diffusible survival/evasion peptide,
  • DCD-1,
  • HCAP,
  • preproteolysin,
  • NM_053283,
  • PIF,
  • DCD
  • identifiers:
  • 117159,
  • ENSG00000161634,
  • DCD

Genome feature

Region: gene ? Length: 3777  
Location: 12:54644589-54648365 reverse strand Cyto location: 12q13.2


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40 SN Ps

5 Cross References

14 Data Sets

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97 Rna Seq Results