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Gene : CLCN4 Homo sapiens

Name  ? chloride voltage-gated channel 4 Cytological Location  Xp22.2
Brief Description  chloride voltage-gated channel 4
Description  The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins. [provided by RefSeq, Mar 2012]
  • synonyms:
  • OTTHUMG00000021125,
  • chloride channel, voltage-sensitive 4,
  • MRX49,
  • X77197,
  • HGNC:2022,
  • CLCN4,
  • ClC-4,
  • MRX15,
  • NM_001256944,
  • uc004csy.5,
  • ClC-4,
  • chloride channel 4,
  • CLC4,
  • MRXSRC,
  • CLC4,
  • ClC-4A
  • identifiers:
  • 1183,
  • ENSG00000073464,
  • CLCN4

Genome feature

Region: gene ? Length: 80716  
Location: X:10156945-10237660 Cyto location: Xp22.2


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Disease

1 Diseases

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3753 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results