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Gene : EXOSC6 Homo sapiens

Name  ? exosome component 6 Cytological Location  16q22.1
Brief Description  exosome component 6
Description  This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation. [provided by RefSeq, Jul 2008]
  • synonyms:
  • MTR3,
  • Mtr3p,
  • Mtr3p,
  • BC052252,
  • Mtr3 (mRNA transport regulator 3)-homolog (yeast),
  • NM_058219,
  • OTTHUMG00000137578,
  • p11,
  • HGNC:19055,
  • p11,
  • EAP4,
  • hMtr3p,
  • hMtr3p,
  • EAP4,
  • MTR3,
  • uc002eym.2,
  • EXOSC6
  • identifiers:
  • 118460,
  • ENSG00000223496,
  • EXOSC6

Genome feature

Region: gene ? Length: 5163  
Location: 16:70246778-70251940 reverse strand Cyto location: 16q22.1

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0 Diseases

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27391 SN Ps

5 Cross References

14 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results