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Gene : CLK2 Homo sapiens

Name  ? CDC like kinase 2 Cytological Location  1q22
Brief Description  CDC like kinase 2
Description  This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
  • synonyms:
  • uc001fjw.4,
  • CDC-like kinase 2,
  • OTTHUMG00000035873,
  • clk2,
  • NM_003993,
  • L29218,
  • HGNC:2069,
  • CLK2
  • identifiers:
  • 1196,
  • ENSG00000176444,
  • CLK2

Genome feature

Region: gene ? Length: 10637  
Location: 1:155262868-155273504 reverse strand Cyto location: 1q22


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Disease

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0 Pathways

2 SN Ps

5 Cross References

16 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results