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Gene : CYP2R1 Homo sapiens

Name  ? cytochrome P450 family 2 subfamily R member 1 Cytological Location  11p15.2
Brief Description  cytochrome P450 family 2 subfamily R member 1
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_024514,
  • Vitamin D 25-hydroxylase,
  • AY323817,
  • cytochrome P450, family 2, subfamily R, polypeptide 1,
  • uc001mlr.4,
  • HGNC:20580,
  • CYP2R1,
  • OTTHUMG00000165900
  • identifiers:
  • 120227,
  • ENSG00000186104,
  • CYP2R1

Genome feature

Region: gene ? Length: 21476  
Location: 11:14877440-14898915 reverse strand Cyto location: 11p15.2

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



309 SN Ps

4 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results