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Gene : CMA1 Homo sapiens

Name  ? chymase 1 Cytological Location  14q12
Brief Description  chymase 1
Description  This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015]
  • synonyms:
  • uc001wpp.2,
  • CYH,
  • chymase,
  • NM_001836,
  • HGNC:2097,
  • MCT1,
  • chymase 1, mast cell,
  • CMA1,
  • OTTHUMG00000140181
  • identifiers:
  • 1215,
  • ENSG00000092009,
  • CMA1

Genome feature

Region: gene ? Length: 2913  
Location: 14:24505353-24508265 reverse strand Cyto location: 14q12


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

3753 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results