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Gene : CCR3 Homo sapiens

Name  ? C-C motif chemokine receptor 3 Cytological Location  3p21.31
Brief Description  C-C motif chemokine receptor 3
Description  The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
  • synonyms:
  • CMKBR3,
  • chemokine (C-C motif) receptor 3,
  • CKR3,
  • uc003cpg.3,
  • CMKBR3,
  • CD193,
  • HGNC:1604,
  • CKR3,
  • CC-CKR-3,
  • CKR 3,
  • AF247361,
  • CD193,
  • NM_001164680,
  • OTTHUMG00000133484,
  • CCR3,
  • C C CKR3,
  • CC-CKR-3
  • identifiers:
  • 1232,
  • ENSG00000183625,
  • CCR3

Genome feature

Region: gene ? Length: 56008  
Location: 3:46210699-46266706 Cyto location: 3p21.31


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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

3753 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results