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Gene : CCR7 Homo sapiens

Name  ? C-C motif chemokine receptor 7 Cytological Location  17q21.2
Brief Description  C-C motif chemokine receptor 7
Description  The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
  • synonyms:
  • CCR-7,
  • CMKBR7,
  • NM_001301714,
  • HGNC:1608,
  • BLR2,
  • CCR7,
  • BLR2,
  • OTTHUMG00000133375,
  • CMKBR7,
  • CDw197,
  • uc002huw.4,
  • CD197,
  • chemokine (C-C motif) receptor 7,
  • CD197,
  • CC-CKR-7,
  • CDw197,
  • EBI1,
  • EBI1
  • identifiers:
  • 1236,
  • ENSG00000126353,
  • CCR7

Genome feature

Region: gene ? Length: 11704  
Location: 17:40553769-40565472 reverse strand Cyto location: 17q21.2


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Disease

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77 SN Ps

5 Cross References

18 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results