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Gene : CCR8 Homo sapiens

Name  ? C-C motif chemokine receptor 8 Cytological Location  3p22.1
Brief Description  C-C motif chemokine receptor 8
Description  This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc010hhr.3,
  • CKR-L1,
  • CC-CKR-8,
  • CY6,
  • CDw198,
  • CMKBRL2,
  • CCR8,
  • CMKBRL2,
  • NM_005201,
  • CCR-8,
  • D49919,
  • chemokine (C-C motif) receptor 8,
  • GPRCY6,
  • CMKBR8,
  • OTTHUMG00000131290,
  • CKRL1,
  • GPR-CY6,
  • CDw198,
  • HGNC:1609,
  • CMKBR8,
  • TER1,
  • TER1,
  • CY6
  • identifiers:
  • 1237,
  • ENSG00000179934,
  • CCR8

Genome feature

Region: gene ? Length: 3972  
Location: 3:39329709-39333680 Cyto location: 3p22.1

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene Ontology

Gene --> GO terms.



42 SN Ps

4 Cross References

15 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results