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Gene : ACKR2 Homo sapiens

Name  ? atypical chemokine receptor 2 Cytological Location  3p22.1
Brief Description  atypical chemokine receptor 2
Description  This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CCBP2,
  • CCR10,
  • ACKR2,
  • CMKBR9,
  • CCR9,
  • D6,
  • CMKBR9,
  • NM_001296,
  • HGNC:1565,
  • chemokine binding protein 2,
  • OTTHUMG00000186377,
  • hD6,
  • CCBP2,
  • CCR9,
  • U94888,
  • CCR10,
  • D6
  • identifiers:
  • 1238,
  • ENSG00000144648,
  • ACKR2

Genome feature

Region: gene ? Length: 57842  
Location: 3:42809445-42867286 Cyto location: 3p22.1

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Gene -> HPO annotation (Human Phenotype Ontology)

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



475 SN Ps

5 Cross References

15 Data Sets

24 Homologues

0 Located Features

97 Rna Seq Results