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Gene : ADH1B Homo sapiens

Name  ? alcohol dehydrogenase 1B (class I), beta polypeptide Cytological Location  4q23
Brief Description  alcohol dehydrogenase 1B (class I), beta polypeptide
Description  The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
  • synonyms:
  • HEL-S-117,
  • NM_000668,
  • AF153821,
  • uc003hus.6,
  • ADH2,
  • ADH1B,
  • OTTHUMG00000161413,
  • ADH2,
  • HGNC:250
  • identifiers:
  • 125,
  • ENSG00000196616,
  • ADH1B

Genome feature

Region: gene ? Length: 16431  
Location: 4:99304971-99321401 reverse strand Cyto location: 4q23

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

19 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results