Name
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cyclic nucleotide gated channel subunit alpha 1 | Cytological Location | 4p12 |
Brief Description | cyclic nucleotide gated channel subunit alpha 1 |
Description | The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Multiple transcript variants have been found for this gene. [provided by RefSeq, Oct 2019] |