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Gene : ADH1C Homo sapiens

Name  ? alcohol dehydrogenase 1C (class I), gamma polypeptide Cytological Location  4q23
Brief Description  alcohol dehydrogenase 1C (class I), gamma polypeptide
Description  This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation to acetaldehyde, thus playing a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. An association between ADH1C polymorphism and alcohol dependence has not been established. [provided by RefSeq, Sep 2019]
  • synonyms:
  • HGNC:251,
  • uc032trd.2,
  • M12272,
  • OTTHUMG00000161422,
  • NM_000669,
  • ADH3,
  • ADH1C,
  • ADH3
  • identifiers:
  • 126,
  • ENSG00000248144,
  • ADH1C

Genome feature

Region: gene ? Length: 16250  
Location: 4:99336497-99352746 reverse strand Cyto location: 4q23

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

18 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results