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Gene : DRAM2 Homo sapiens

Name  ? DNA damage regulated autophagy modulator 2 Cytological Location  1p13.3
Brief Description  DNA damage regulated autophagy modulator 2
Description  The protein encoded by this gene binds microtubule-associated protein 1 light chain 3 and is required for autophagy. Defects in this gene are a cause of retinal dystrophy. In addition, two microRNAs (microRNA 125b-1 and microRNA 144) can bind to the mRNA of this gene and produce the disease state. [provided by RefSeq, Mar 2017]
  • synonyms:
  • OTTHUMG00000011911,
  • transmembrane protein 77,
  • RP5-1180E21.1,
  • WWFQ154,
  • uc001ead.5,
  • PRO180,
  • DRAM2,
  • AY336747,
  • TMEM77,
  • HGNC:28769,
  • MGC54289,
  • TMEM77,
  • CORD21,
  • NM_178454,
  • PRO180,
  • WWFQ154,
  • DNA-damage regulated autophagy modulator 2
  • identifiers:
  • 128338,
  • ENSG00000156171,
  • DRAM2

Genome feature

Region: gene ? Length: 23047  
Location: 1:111117170-111140216 reverse strand Cyto location: 1p13.3


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

3753 SN Ps

5 Cross References

17 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results