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Gene : COPA Homo sapiens

Name  ? COPI coat complex subunit alpha Cytological Location  1q23.2
Brief Description  COPI coat complex subunit alpha
Description  In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • synonyms:
  • U24105,
  • HEP-COP,
  • OTTHUMG00000033111,
  • proxenin,
  • AILJK,
  • coatomer protein complex, subunit alpha,
  • HEP-COP,
  • alpha-COP,
  • uc009wti.4,
  • HGNC:2230,
  • xenin,
  • NM_004371,
  • COPA
  • identifiers:
  • 1314,
  • ENSG00000122218,
  • COPA

Genome feature

Region: gene ? Length: 54657  
Location: 1:160288594-160343250 reverse strand Cyto location: 1q23.2


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1 Diseases

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3753 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results